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Enterovirus D68: How Can You Keep Your Children Safe?

By: Wieke von Scheidt
Enterovirus

With the start of the Fall season the flu is not the only highly contagious disease we need to worry about.  People are getting  increasingly concerned about a virus, called Enterovirus D68 that is slowly making its way from state to state. Parents are particularly worried because it affects children more often than adults.  The symptoms start out with a mild cold to later become more severe, affecting children’s respiratory system.

What is it?

Enteroviruses have been around for a long time, usually causing colds, fever, headaches, vomiting, and rashes in addition to other symptoms. EV-D68 is an unusual strain causing more severe symptoms such as wheezing and difficulty breathing. This may cause particular concerns for parents with children who have lung problems or asthma because it is harder to recognize. In some cases kids had been hospitalized because they required mechanical ventilator in order to breathe properly. The Center of Disease Control is paying close attention to the development of this virus.

How can you get it?

D68 is spreading like many other viruses through body fluids, like saliva, nasal secretion, as well as other kinds of interactions. The time of year Enteroviruses seem to affect more people is in the Summer and the numbers decrease in the Fall.

How to protect yourself?

  • Keep away from sick people
  • Wash hands often with soap and warm water for about 20 seconds
  • Don’t put backpacks, purses, jackets or other items on restroom floors and counters.
  • Pack reusable water bottles instead of using public water fountains.
  • Carry hand sanitizer with you
  • Don’t share bottles, and utensils
  • Wipe down surfaces with disinfectant wipes
  • Avoid hugging and kissing while being sick

How to treat it?

There is no vaccine or specific medication to treat Enteroviruses. All that can be done is to relief patience of symptoms through mechanical ventilators, and over-the-counter medications for pain and fever. Therefore it is important for parents to take be cautious and take preliminary actions to avoid infections.

For more detailed information visit Centers of Disease Control http://www.cdc.gov/non-polio-enterovirus/index.html

http://www.health.harvard.edu/blog/protecting-children-enterovirus-d68-201409227455
http://childrenshospitalblog.org/what-to-know-about-enterovirus-d68/
http://www.cdc.gov/non-polio-enterovirus/about/ev-d68.html

How to Stay Healthy While Traveling

By Wieke von Scheidt

Summer is almost here, or at least we hope it is. This is the time of year when many take vacation to travel, and relax. Kids have long breaks and parents can use up some of their vacation days. If you are traveling this summer it’s a good thing to know some ways to stay fit. Health is something that is often forgotten while traveling. On your next trip try to keep some of these tips in mind.

Explore the Area

Before you travel, plan your trip. Buy a map or a travel guide with interesting places to visit. Once you get to your destination be sure to get out of your accommodation at least once a day and walk around outside. Going for a long walk, whether you are exploring the city, or strolling along the beach is a great way to relax the mind and keep your body going. If it’s raining you can visit museums, shopping centers, or other indoor places that allow you to walk around.

Eat Healthy

While on vacation it is always easy to just get a quick meal from any fast food restaurant, but it is better to take an extra five minutes to bring your own meal. It will also be better for your wallet. For the little hunger in-between you can pack snacks like apples, bananas, and my personal favorite, granola bars. If you still decide to go out to eat choose a restaurant that serves a variety of good foods and make sure to get some vegetables with your meals.

Be Active

Many hotels have amenities such as gyms, swimming pools, tennis courts, and so on. Even if the place you stay at does not offer any of these services, get creative. If the weather is nice, plug your headphones in and go out for a run, hike, or rent a bike. This is also a great way to explore the area.

Take the Stairs

If you stay in a room that is a couple floors up, and not all the way in the sky consider taking the stairs instead of the elevator. Have you been sitting all day, or spent a lazy day lounging by the beach? It will feel good to walk some stairs and maybe stretch. Anywhere you go you will probably find stairs, so make it a habit to use them.

Bring a Workout DVD

In case your hotel does not have any amenities you can always bring some workout DVDs and exercise in your room. Many hotel rooms have DVD players, or you can just bring your own laptop. This is a great way to get a quick workout in, especially if you don’t like exercising around people.

Vacations are a wonderful time to disconnect from our busy lives and truly relax. This does not mean you should take a break from your healthy lifestyle you normally follow. If you are used to working out and staying fit, don’t blow all that hard work by skipping it completely during your vacation. And if you love staying active it should not be a hard task to keep it up while traveling. Do you have any tips on how to stay fit and healthy while traveling? Share your tips and tell us how you stay active below, on our Facebook, or Tweet us.

The CLAREX EFFECT (Concise)

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Food for Thought for the Holidays

By Eugene Y. Chan, MD

The holidays are approaching us fast and typically there are two big fears that confront us:  (1) how do I not gain weight? and (2) how do I survive my holiday party?  Thanksgiving and the holidays are synonymous with gluttony, binge eating, and over indulgence.  Furthermore, there are numerous holiday parties that you need to attend, whether out of obligation or for fun.  Given the joyous time of year, there is plenty of opportunity to get carried away.  Fortunately, there is time to prepare.  

First, regarding weight gain, there are several key realizations.  The first is that the stomach has unique properties.  It is an expandable container, made of smooth muscle.  If it is in a compact state for weeks prior to your binge eating episode, you will feel full faster and will not consume as much.  On the flip side, if you occasionally have large meals, you stomach will have lost its elasticity, very much like a balloon that has been inflated and deflated multiple times, and you will be able to consume a lot more.  Second, your stomach and digestive tract secrete enzymes that require a certain time of upregulation, through gene expression and protein translation.  Without certain key enzymes, the nutrients of certain foods do not make it into the body.  So you could utilize this to your advantage.  If you avoid fatty foods routinely, it is unlikely that a single meal of fatty foods will lead to significant weight gain.  The lesson here in understanding the anatomy of your stomach as well as the molecular response of it to food is simple:  if you eat healthy and in small portions on a routine basis, the impact of a single large meal is unlikely to have significant impact on your daily trip to the scale.  Of course, it all goes without saying that you should continue to remain active and exercise often.

Ok, what should you do about those holiday parties?  Holiday parties tend to be a great time to network, build camaraderie with your colleagues, all through a relaxed atmosphere.  Part of this is a liberal amount of beer, wine, and cocktails that loosen up even your stiffest co-worker.  The key here is moderation for you.  Since you don’t want to be the individual that gets talked about the day after, setting a drink limit and goal for yourself prior to the party is most important.  Discussing your goals with a colleague of similar professional mindset would help you solidify your resolve.  In the event you did have one too many, how do you make it to work?  The answer is simple:  drink plenty of water and take a product designed for post-celebration recovery.  The key is to get your Kreb’s cycle back up and running since an excess of ethanol builds up NADH, which signals the Kreb’s cycle to slow down.  As you know the Kreb’s cycle is central to generating ATP, your body’s main form of energy.  By supplementing key cofactors for enzymes in your Kreb’s cycle, you can get it back up and running in no time, and feel great in the process.  

With that, good cheers for the holidays and be well.

 

A Lethal Dose of Caffeine

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By Eugene Y. Chan, M.D.

Recent news about tragic death of Anais Fournier hit the web.  She was 14 and she died after consuming two 24-ounce Monster Energy drinks over a 24-hour period.  She had an underlying heart arrhythmia that may have predisposed her to the adverse effects of caffeine.

Caffeine is a small molecule alkaloid that is found in many different types of plants.  It has a receptor-based mechanism of action that antagonizes the action of adenosine.  In clinical medicine, adenosine is sometimes utilized to treat certain irregular heartbeats, including some supraventricular tachycardias.  Decreasing the action of adenosine can therefore lead to a faster heart rate and can also predispose the heart to irregular heartbeats.  In the case of the very unfortunate 14-year old, she consumed caffeine which decreased action of the adenosine, thus increasing her likelihood of a fatal arrhythmia.

How much is too much?  One may say, “Let us calculate the lethal dose.”  The LD50, or lethal dose for killing 50% of tested animals, for rats is 192 mg/kg.  Extrapolating this to a 14-year old weighing 50 kg, this LD50 is 9.6 grams of caffeine.  Of course, these studies were not conducted in humans so this is only a ballpark estimate.  In a typical energy drink, there is approximately 200 – 300 mg of caffeine, although in some energy drinks, the actual amount is unclear, based on how the products are labeled.  We can assume that Anais probably consumed < 1 gram of caffeine from her two energy drinks, yet this was a fatal dose for her.  What the LD50 calculation is missing is both an understanding of both statistics as well as pharmacogenomics.  Statistics tells us that some individuals may very well have adverse events at a much lower dose of caffeine.  Part of this is based on a genetic makeup and how we react to certain molecules.  This is called pharmacogenomics.  In the case of Anais, she likely had a genetic cause of her underlying cardiac arrhythmia.  She may very well have been a slow metabolizer of caffeine, also based on her genetic makeup, leading this molecule to linger in her system much longer than that of her counterparts.  Without a whole genome study, of course, we would never know.

Overall, the lesson here is that receptor-based molecules, such as caffeine, can be extremely dangerous, depending on the specifics of your medical and genetic background.  For most people it may be fine, for others, it can unfortunately take push you over the threshold of safety.

Why you need mental clarity

By Eugene Y. Chan, MD

Somewhere around 3 AM in the morning at the Massachusetts General Hospital one day, I remember a particular instance of having to draw blood from a very ill patient.  By that time, I had already worked for 20 hours straight, with my beeper ringing every few minutes.  What is so urgent that requires a blood draw at this hour?  I looked at the patient’s medical record and saw a history of HIV and HCV.  This patient was in renal and liver failure.  I looked for a suitable vein in the antecubital fossa but could not find any.  I look elsewhere on the arm, but still no.  My eyes were feeling heavy from my day and also staring closely in the dark to look for a thin blue vein that I could target.  Finally, I found a potential vein, on the dorsal surface of the foot.  It was so thin and collapsed, but it was my only hope.  I knew that if I were not careful, I could indeed inadvertently stick myself, which could put me at risk for both HIV and HCV.  I also knew that I did not draw the patient’s blood, she would have a high likelihood of not making it through the night.  It is in times like this, where if your mind wanders, even for a brief moment, the outcome would be highly undesirable.  This is when you need mental clarity, this is when you need that moment of unwavering focus.  Have you been in a circumstance like this?  Maybe not treating a patient, but interviewing for a most coveted job, giving the most important sales presentation, or pushing yourself to win that race?  Fortunately, the outcome that morning was positive, the important medical tests were highly informative for the course of her care and the patient made it through the night.  There are situations like that that arise often, and often unexpected, and you have to be prepared to make those yours.  Stay focused and be at your best, always.

Clarex’s Busy Weekend!

Clarex was all over the place this past weekend. We were at the Whole Foods in Cambridge and Newton, cheering on bicycle riders as they began a trip from Boston to Raleigh, handing out samples with HubHelmet and even at Fenway Park! Clarex was stocked on the shelves, and great times were had by all.

The day began as early as 8 for our Street Team, who were up bright and early to attend the The Pablove Foundation’s long-distance bike ride.It funds pediatric cancer research and programs to improve the quality of life for children living with cancer.The 1000-mile bike ride from Boston to Raleigh began with a nice breakfast for riders, family, and supporters to chat and enjoy at the Whole Foods on Prospect St. in Cambridge. Not to mention we had our team there handing out samples and taking photos of the event, which you can view here. The kickoff also had another perk for Clarex-our product was officially on the shelves! What an accomplishment! So be sure to visit the Whole Foods on Prospect St. to buy Clarex directly along with your other groceries.

Meanwhile, Captain Clarex was at the Whole Foods in Newton, setting up his demo. Clarex is also now sold at the Whole Foods in Newton, and many people got to learn about eliminating mental limits with Clarex. There were trial sizes to test out, and the product being sold right there in the store for those who wanted to continue to increase their focus. After all, Clarex is all natural and caffeine-free!

We also had some samples to give away with HubHelmet, a new service that allows Hubway users access to helmets for safe riding. Be sure to look out for HubHelmet available with all Hubway stations soon! Clarex was a big hit, and it’s great for bike riding so you can focus more on your ride and enjoy it.

Clarex was also at Fenway Park this Saturday as well! After attending teh Pablove Foundation’s kickoff event, Team Clarex attended College Day @ Fenway. where lots of college students received samples. Everyone there had a fantastic time, especially our street team members who got to pose with the World Series trophies! Check out the photos here.

And to think this is just the beginning! Keep on the lookout for Clarex on our Facebook page to learn where we will be next. Comment with any suggestions or feedback-we love to hear from our fans!

-Team CLAREX

Breaking Down the Intelligent Workout with Eric Ballenger

Eric Ballenger

Welcome to the Clarity Corner! I’m Eric Ballener, and a daily Clarex user. As a fitness enthusiast, my background includes ISSA, ACE, NFPT certified, certified personal trainer, former NPC competitor, and a Pre-Contest Prep Coach. I’ll be posting regularly with all things fitness, so check back often! Feel free to comment with any questions to answer in future posts.

What we do before we work out can be just as important as any exercise we do during our workout. Pre-workout preparation has been studied, dissected, and argued about since before Arnold lifted his first barbell. .Let me back up here for a second, we’re not just talking about the gym rats. (You know who you are, because I’m one too!) I’m talking about the triathlete, the cyclist, the runner, the CrossFit enthusiasts, the powerlifter, and even the bodybuilder. We are all familiar with the term “muscle memory.” Muscle memory has been used along simultaneously with motor learning, which is a form of procedural memory that involves consolidating a specific motor task into memory through repetition.

In other words, every Monday, we wake up thinking today is chest day and our mind prepares our body for the trauma that it will endure during a typical workout. We have all been there. We take the thermogenic gotten the jitters the heart palpations the sweats but what did we really accomplish? We have once again attacked our receptor sites and overstimulated our adrenal glands.  Through the use of Clarex, I have personally found a new form of laser focus while in the gym. Though I still enjoy my heavily caffeinated and synephrine based pre-workout RTD, I have now added Clarex as a complement to my regimen.

This is where “The Intelligent Workout” begins. I take my Clarex with my thermo 30-45 minutes pre-workout. The most profound and lasting impact of Clarex on my workout is found in the level of clarity that did not exist before, I no longer find myself asking what exercise is next. Rather, I find myself with that feeling of complete focus and concentration.

As a result, my workouts have become more intense, and shorter in duration. Let me reiterate. CLAREX IS NOT A THERMOGENIC! Clarex is a stimulant-free complement to any pre-workout regimen. Clarex, when taken as directed, can help you get the most out of every workout no matter what hurdles life has thrown at you before you step through the gym doors. So try Clarex today, “Eliminate YOUR Mental Limits” and unlock your body’s full potential with no side effects and no crash.

-Team CLAREX

Jon Chafe

Jon Chafe

Meet Jon Chafe, our CLAREX representative in Canada. We are very excited to have Jon as part of our team here at CLAREX. An avid user, Jon has improved his focus and gotten the most out of his workouts.

-Team CLAREX

Clarex Review

Logan Gelbrich, contributor of Breaking Muscle, wrote a review regarding his experience with Clarex. Breaking Muscle is a website dedicated to fitness and provides articles, product reviews, exercises to try out, and videos with proper form. On the site, Gelbrich breaks down the product, explaining what Clarex does along with his positive Clarex experience. 

Check out the link for yourself, and let us know what you thought in the comments.

-Team CLAREX

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